代表性成果

The divergent restoration effects of Lactobacillus strains in antibiotic-induced dysbiosis

作者：Y Shi，L Kellingray，GL Gall，J Zhao，H Zhang，A Narbad，Q Zhai，W Chen摘要：To evaluate functions of Lactobacillus strains, isolated from fermented food, in restoration of ampicillin-induced disruption based on mucosal barrier, gut microbial community and metabolome analyses, three Lactobacillus strains, L. plantarum CGMCC12436 (LacP), L. casei CGMCC 12,435 (LacC) and L. rhamnosus strain...

In vitro and in vivo evaluation of Lactobacillus strains and comparative genomic analysis of Lactobacillus plantarum CGMCC12436 reveal candidates of colonise-related genes

作者：Y Shi，J Zhao，L Kellingray，H Zhang，A Narbad，Q Zhai，W Chen摘要：The presence of Lactobacillus strains in dairy products and the intestinal tracts of humans and animals is frequently considered to have beneficial effects on gut health. In this study, five L .plantartmt and five L. casei strains from fermented food origin were isolated and compared to characterise their functional prope...

Comparative Genomics of Lactobacillus crispatus from the Gut and Vagina Reveals Genetic Diversity and Lifestyle Adaptation

作者：Q Zhang，L Zhang，P Ross，J Zhao，W Chen摘要：Lactobacillus crispatus colonizes the human feces, human vagina, and the crops and ceca of chicken. To explore the genetic characteristics and evolutionary relationships of L. crispatus isolated from different niches, we selected 37 strains isolated from the human vagina (n = 17), human feces (n = 11), and chicken feces (n = 9), and used compa...